The Best Anti-Aging Supplements You Can Buy

Edited and medically reviewed by ✔️ Team of BestInSupplements | Written by Katelyn Johnson (B.S. and M.S. in Nutrition Science)

Aging is hard, so we compiled a list of the best anti-aging supplements that are highly regarded by those who use them on a daily basis. Discover which ones are the best to buy.

Best anti aging supplements

Most people would like to slow the process of aging, which is defined as the “time-related deterioration of the physiological functions necessary for survival and fertility”. That is why the best anti-aging supplements have gained such popularity in recent years.

The accumulation of cellular damage caused by reactive molecules known as free radicals, as well as the shortening of telomeres, which are structures located at the ends of chromosomes that play an important role in cellular division, are two of its main causes 1.

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While aging is unavoidable, scientists have been working for decades to extend human life and slow the aging process. Currently, a large number of substances with anti-aging properties have been identified as a result of their research. Many of which can be taken as supplements by those looking for natural ways to slow the aging process and prevent age-related disease.

Research consistently shows that proper nutrition, including a diet high in antioxidants and omega-3 fatty acids, can have anti-aging benefits such as cancer prevention, shiny hair, clear skin, faster brain function, and increased energy 3.

Best Anti-Aging Supplements On The Market

However, as an additional preventative measure, including anti-aging supplements in your diet can be a simple and effective way to reap these benefits. Let’s take a look at some of the best alternatives you can find in the market.

Best For High Cholesterol: Nordic Naturals Ultimate Omega SoftGels

Omega-3 supplementation has been shown to reduce the shortening of telomere DNA sequences, which shorten with age and is associated with age-related disease 3.

Nordic Naturals Ultimate Omega

Nordic Naturals Ultimate Omega SoftGels contain the essential fats EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid), which have been shown to improve the health of the heart, brain, joints, eyes, and mood in over 14 clinical trials 3.

And, according to reviewers, the supplement helped with everything from high cholesterol to anxiety to lupus symptoms.

Nordic Naturals Ultimate Omega Reviews, Ingredients, Does It Work?
In this review of Nordic Naturals Ultimate Omega, we cover its ingredients and benefits to help you determine if this is the supplement for you.

Best Anti-Aging Vitamin: Nature Made Vitamin C

Vitamin C is a common recommendation among experts. This nutrient promotes youthful skin, aids in collagen production, and has antioxidant properties that help fight cancer 4. After being damaged by sunlight, vitamin C actually knits the collagen structures back together.

Nature Made Vitamin C

If you don't get enough vitamin C, your collagen won’t hold together properly, resulting in wrinkles and crevices. So even if you have all the collagen in the world, without vitamin C, you won't be able to finish the process of linking collagen together.

The Nature Made Vitamin C supplement is highly recommended, and those looking for the full effect should take a 1000 mg extended time-release vitamin C.

Nature Made Vitamin C Reviews, Ingredients, Does It Work?
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Best Collagen Peptide: Live Conscious (LiveWell) Collagen Peptides

Collagen Peptides from Live Conscious contain both types I and III collagen. It also contains 20 amino acids, making it one of the most diverse amino acid profiles available today. Collagen and amino acids both work to support overall health and wellness, especially benefiting the skin and connective tissue 5.

Live Conscious (before LiveWell) Collagen Peptides review

Collagen is an important component of connective tissue, which provides structure to many parts of the body such as bones, skin, tendons, and ligaments. Collagen, in essence, helps to keep the skin plump and firm. Amino acids’, such as proline and lysine, aid in the stabilization of collagen against free radical damage 5.

Live Conscious Collagen Peptides also contain calcium, magnesium, and other important minerals that work together to support your bones and joints while also strengthening your hair and nails and supporting healthy weight management 5.

There are no hidden additives, fillers, or artificial ingredients in this product. It has also been tested by a third party. The return policy is excellent, with a 365-day, risk-free money-back guarantee demonstrating that the company stands behind its products.

Live Conscious (LiveWell) Collagen Peptides Reviews, Ingredients, Does It Work?
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Best For Fine Lines and Wrinkles Reduction: SeroVital

SeroVital is a daily nutritional supplement supported by 25 years of anti-aging research, asserting it can increase growth hormone (hGH) levels up to 682 percent. High hGH levels have been linked to a reduction in the appearance of fine lines and wrinkles, a reduction in body fat, increased energy, and improved sleep and mood 6.

Therefore, SeroVital offers a wide range of anti-aging benefits, as well as mood enhancement, weight loss assistance, and sleep improvement 6.

Many SeroVital Advanced users discovered several advantages to taking the supplement in the morning and at night. Additionally, many claim they have lost weight, have more energy throughout the day, their skin has less wrinkles, and most importantly, their sleep is restful and complete.

Serovital Reviews, Ingredients, Does It Work?
At this review of SeroVital we discuss the benefits and ingredients and find out if they are effective and safe.

Best Collagen Powder: Multi Collagen Powder Ancient Nutrition

Ancient Nutrition, as the name suggests, incorporates time-honored practices from Traditional Chinese Herbalism and Ayurveda. The Multi Collagen Protein blends collagen from five different sources, including bovine, fish, chicken bone broth, and eggshell membrane.

Ancient Nutrition Multi Collagen

The hydrolyzed collagen in the Multi Collagen Powder provides a diverse blend of beneficial amino acids rarely found in one supplement. This product is intended to improve gut function, support joints, and enhance appearances, such as toned skin and strong nails 7.

Ancient Nutrition Multi Collagen Reviews, Ingredients, Does It Work?
Do you want to discover if Ancient Nutrition’s Multi Collagen works? You will read here the best review with ingredients, opinions and all related to this supplement from Ancient Nutrition.

If you want a product with a wide range of beneficial properties, very few ingredients (only four!) and no flavorings or sweeteners, stick to the original Multi Collagen Protein.

Best For Inflammation: ENERGYbits Spirulina Tablets

Spirulina Algae is a nutrient-dense, high-protein, plant-based, sustainable, safe, and organic food source. EnergyBits Spirulina Algae is extremely beneficial to humans and notably one of the best anti-aging supplements because it acts as an antioxidant, immune booster, and anti-inflammatory agent 8.

Energybits Spirulina Algae Tabs

This product safely and efficiently satisfies hunger, supplements numerous daily nutritional needs, boosts energy, focus, and even athletic performance. It also delivers natural detoxification and chelation, strengthens cardiovascular, neurological, immune, and mental health, and increases longevity and wellness 8.

Energybits Spirulina Algae Tabs Reviews, Ingredients, Does It Work?
Are Energybits Spirulina Algae Tabs effective? What are the ingredients? What are people's thoughts? That is what you will discover if you read our review of this supplement.

Best For Cellular Energy Production: Life Extension NAD+ Cell Regenerator

Nicotinamide Riboside (NAD+) is a cellular coenzyme found in all of our bodies' cells. NAD+ is required for the production of adenosine triphosphate (ATP), which is the body's primarily fuel source.

Life Extension NAD+ Cell Regenerator

NAD+ Cell Regenerator contains 100 mg of NIAGEN, which is the first commercially available form of nicotinamide riboside, said to help fight fatigue at the cellular level 9.

Life Extension’s NAD+ Cell Regenerator has been shown to improve cellular metabolism and energy production, aid in the prevention of general fatigue and the promotion of longevity, and in preclinical studies, promote youthful cognitive function 9.

Life Extension
Life Extension supplements have been produced with the hope that these will be able to supply all deficient nutrients in the body and help gain better health.

Best Anti-Aging: Supplement & Cell Rejuvenation From Tru Niagen

Nicotinamide adenine dinucleotide (NAD) is a critical component in cellular energy production. It is involved in metabolic pathways that contribute to things like sleeping, breathing, and eating, as well as other vital functions like DNA and cellular repair.

Tru Niagen Age Better

The amount of nicotinamide adenine dinucleotide (NAD) produced by our bodies decreases dramatically as we age. Some studies indicate a 50% drop in NAD levels between the ages of 40 and 60 2. That is where the brand Triu Niagen can help you.

Low NAD levels are linked to an increased risk of heart disease, high blood pressure, type II diabetes, Alzheimer's disease, and accelerated aging 2. Therefore, it is theorized that NAD+ deficiency is one of the primary reasons why people age 2.

According to the company Triu Nagen, supplementing NAD can improve energy in living cells and prevent the physiological effects of aging.

Tru Niagen is the leading brand, selling potent, powerful NAD supplements. Their patented product is said to promote cellular repair, counteract the effects of exercise, stress, and aging on the body.

If you are looking for a reliable NR supplement, Tru Niagen may be the best option and the market's current number one anti-aging supplement.

Best Resveratrol: Thorne Research ResveraCel

It has been suggested that drinking a glass of red wine every night keeps your heart healthy. Few compounds found in red wine have received as much attention and have yielded as many promising results as resveratrol 10.

Thorne ResveraCel

Resveratrol stimulates and increases sirtuin activity, which has been demonstrated to slow and reverse the aging process. Numerous studies have shown that resveratrol is beneficial to overall health because it has the ability to mimic the effects of calorie restriction by decreasing insulin sensitivity, restoring cardiovascular health, and encouraging autophagy.

Thorne Research's ResveraCel is one of the best resveratrol supplements on the market today. It contains a significant amount of naturally sourced resveratrol as well as other beneficial sirtuin-activating compounds found in red wine. Their resveratrol supplement ResveraCel has been shown to aid in the reduction and minimization of wrinkles, as well as the ability to slow cognitive deterioration.

Frequently Asked Questions

Anti-aging supplements are remedies that assist and manage your body's natural processes through the combination of nutrients, vitamins, minerals, and herbs. While the benefits of these supplements are diverse, anti-aging supplements primarily function to decrease inflammation, protect against oxidative stress, and enhance cell regeneration.
Researchers identified a number of compounds with anti-aging effects, many of which are offered in supplement form for anyone interested in natural ways to slow down the aging process. The main ingredients used include omega 3 fatty acids, nicotinamide adenine dinucleotide (NAD), collagen, and resveratrol.
Although it’s ideal to understand which health benefit you’re looking for, when shopping for the best anti-aging supplement, search for items that have strong antioxidant and anti-inflammatory properties. These key properties combat aging by promoting skin cell longevity, collagen formation, and free radical protection.
There are many forms of anti-aging supplements available to purchase on the market. Depending on your nutritional needs, and which part of the anti-aging process you are trying to target, anti-aging supplements are equally as effective in tablet, powder, drop, pill or capsule forms.
Purchase from trustworthy companies and select supplements that have been tested by a third party to confirm their safety, purity, and effectiveness. Make sure to review the supplement labels thoroughly. To get the most value for the money, avoid products that contain a lot of sugar, synthetic substances, or additives.
Although some supplements may be advantageous as you age, it's necessary to recognize that supplements aren't for everyone. Common side effects experienced include dizziness, nausea, and high blood pressure. For individuals with special health issues, some supplements can interact with prescriptions or create dangerous negative effects.


  1. Jennings, B. J., Ozanne, S. E., & Hales, C. N. (2000). Nutrition, oxidative damage, telomere shortening, and cellular senescence: individual or connected agents of aging?. Molecular genetics and metabolism, 71(1-2), 32-42.
  3. Mazza, M., Pomponi, M., Janiri, L., Bria, P., & Mazza, S. (2007). Omega-3 fatty acids and antioxidants in neurological and psychiatric diseases: an overview. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 31(1), 12-26.
  4. Bsoul, S. A., & Terezhalmy, G. T. (2004). Vitamin C in health and disease. J Contemp Dent Pract, 5(2), 1-13.
  5. Czajka, A., Kania, E. M., Genovese, L., Corbo, A., Merone, G., Luci, C., & Sibilla, S. (2018). Daily oral supplementation with collagen peptides combined with vitamins and other bioactive compounds improves skin elasticity and has a beneficial effect on joint and general wellbeing. Nutrition Research, 57, 97-108.
  6. Medeiros, A., & Siegel Watkins, E. (2018). Live longer better: the historical roots of human growth hormone as anti-aging medicine. Journal of the history of medicine and allied sciences, 7 3(3), 333-359.
  7. Lupu, M. A., Gradisteanu Pircalabioru, G., Chifiriuc, M. C., Albulescu, R., & Tanase, C. (2020). Beneficial effects of food supplements based on hydrolyzed collagen for skin care. Experimental and therapeutic medicine, 20(1), 12-17.
  8. Barkia, I., Saari, N., & Manning, S. R. (2019). Microalgae for high-value products towards human health and nutrition. Marine drugs, 17(5), 304.
  9. Braidy, N., & Liu, Y. (2020). NAD+ therapy in age-related degenerative disorders: A benefit/risk analysis. Experimental gerontology, 132, 110831.
  10. Singh, A. P., Singh, R., Verma, S. S., Rai, V., Kaschula, C. H., Maiti, P., & Gupta, S. C. (2019). Health benefits of resveratrol: Evidence from clinical studies. Medicinal research reviews, 39(5), 1851-1891.

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