Omega XL Reviews, Ingredients, Does It Work?

Edited and medically reviewed by ✔️ Team of BestInSupplements | Written by Katelyn Johnson (B.S. and M.S. in Nutrition Science)

Omega XL is a popular fish oil supplement. But, is it the right one for you? We conducted an in-depth analysis of this product to help you decide if it’s safe to use, how it works, and the quality of its ingredients.

Review of Omega XL

Omega-3 supplements like Omega XL are must-have products in almost every wellness routine. Omega XL is an omega-3 dietary supplement composed of over 30 different naturally sourced fatty acids. This product sources their essential fatty acids from green-lipped mussels, rather than fish or algae - which are the common sources in fish oil supplements that give the fishy aftertaste.

These essential healthy fats, which have been extensively researched and studied for their whole body supporting benefits, are critical for human development and healthy aging, as well as cognitive, heart, joint, skin, and overall health 1.

Omega-3 fatty acids must be consumed through diet or supplementation because your body cannot produce them on its own. Despite its importance in every aspect of human health, most people's diets are severely lacking in this healthy fat 1. That's why an increasing number of people are turning to fish oil supplements like Omega XL to obtain all of the omega-3s they require on a daily basis in a safe and effective manner.

Omega XL Benefits

Omega XL comes from New Zealand's pristine waters, which are said to be among the cleanest on the planet. The Omega XL formula is toxin-free and is shown to fight free radicals, while improving joint health, mobility and vitality.

Improves Joint Health and Reduces Inflammation

Joint pain can occur for a variety of reasons. Most people attribute it to the natural aging process, though injuries, genetics, and lifestyle choices can also play a role. Joint pain and inflammation, regardless of the cause, can have a significant impact on your quality of life, which is why finding a quick and safe solution like Omega XL is critical 2.

Because of the green-lipped mussel extract, PCSO-524 TM, which has been found to be an effective ingredient for treating joint pain and rheumatoid arthritis in clinical studies, Omega XL may be more beneficial than fish oil for some users 2.

Vitamin E and Perna Canaliculus Proprietary Oil Extract are two potent anti-inflammatory agents found in the product. These help to alleviate the pain and inflammation associated with arthritis. Vitamin E deficiency is common in elderly people with osteoarthritis, so a supplement like Omega XL may be beneficial 3.

It's also high in antioxidants, which help the body's natural healing process and strengthen immunity. Antioxidants play an important role in reducing oxidative stress in the body, according to a review published in Nutrition Journal 3. Omega XL is said to help with back pain by reducing inflammation in the body. This supplement may be beneficial for fibromyalgia sufferers, as omega-3 fatty acids may help alleviate symptoms 4.

Improves Brain Health

EPA and DHA are two important fatty acids found in Omega-3 and DHA accounts for nearly all of the omega-3 fatty acids in your brain 5. In the central nervous system, both EPA and DHA play crucial biological roles. DHA is a significant structural component of neuronal membranes, and altering the fatty acid content of these membranes causes functional alterations in neuron receptor activity. The physiological activities of EPA can influence neuronal activity.

Biochemical investigations have demonstrated decreased amounts of omega-3 fatty acids in red blood cell membranes in both depressed and schizophrenic individuals, indicating a link between depression and poor dietary intake of omega-3 fatty acids 5.

Improves Cardiovascular Health

Omega XL contains omega-3 fatty acids, which are said to be beneficial to heart health. These fatty acids can help thin your blood, which can help lower blood pressure. Because of the omega-3 fatty acids in Omega XL, it may help lower cholesterol levels by reducing triglycerides levels in the blood.

Omega-3 fatty acids can also help lower the risk of stroke and heart failure because they are shown to reduce body inflammation and plaque growth in your arteries 6.

Omega XL Ingredients

Ingredients of Omega XL

Omega XL is an omega-3 fatty acid supplement that contains a combination of natural ingredients extracted from non-animal sources.

Perna Canaliculus Proprietary Oil Extract

This is the oil from a shellfish known as New Zealand Green-Lipped Mussel. The potent anti-inflammatory properties of this compound, as well as its effectiveness in treating joint problems, were discussed in an article published in the Internet Journal of Alternative Medicine. According to this study, Perna Canaliculus Green-Lipped Mussel Extract, or PCSO-524, is 89 percent more effective than regular fish-based supplements for easing joint pain 7.

Take a look at this alternative: Relief Factor Reviews, Ingredients, Does It Work?

Omega-3 Fatty Acids

These fatty acids are known for relieving joint pain, and some research suggests that they may also act as a natural anti-inflammatory 8.

Vitamin E

Vitamin E is a fat-soluble vitamin found in a variety of foods, including olive oil. This vitamin has a variety of health benefits, including improving skin and nail health. It also has anti-inflammatory and antioxidant properties. Vitamin E's role in preventing and treating osteoarthritis was discussed in an article published in Frontiers of Pharmacology 9.

Natural Monounsaturated Olive Oil

Monounsaturated olive oil - derived from the olive tree - contains an abundance of monounsaturated fats and known as one of the healthiest fats available. Monounsaturated fatty acids (MUFAs) have been shown to reduce total and low-density lipoprotein (LDL) cholesterol levels 10.

Furthermore, some research suggests that MUFAs may help with insulin levels and blood sugar control, which can be beneficial if you have type 2 diabetes or are at risk of developing it. Additionally, monounsaturated fats, according to the Mayo Clinic, can lower your risk of heart disease and cholesterol levels 10.

They have been shown to aid in the treatment of rheumatoid arthritis. Olive oil was found to be effective in treating pain in women with arthritis in a study published in Rehabilitation Nursing 11.

Omega XL Safety and Side Effects

Ingredients derived from milk, yeast, corn, gluten, allergen protein, and artificial sources are not found in Omega XL.

The manufacturer's website contains no information about the product Omega XL's potential side effects. However, according to other websites, some people may experience nausea, gas, and diarrhea after consuming the product.

Even though the manufacturer claims it's free of shellfish, one of the ingredients is. If you have a shellfish allergy, be cautious.

Customers who are taking any medications should consult with their healthcare provider before using this product.

Who Should Buy Omega XL

Omega XL is a potent omega-3 joint health supplement that contains highly beneficial and healthy fatty acids - including both DHA and EPA - which have been shown to help relieve joint pain caused by inflammation.

This joint health dietary supplement was created to act as a pain reliever for those who are experiencing pain as a result of injury, inflammation, or other health conditions such as rheumatoid arthritis and osteoarthritis. It can also aid in the maintenance of respiratory health and pain management.

Another Related List You Might Like: The Best Keto Supplements You Can Buy

As a result, taking this supplement will help anyone who is, or wants to, lead a healthy and active lifestyle.

Omega XL is available in soft gel capsules, which most seniors prefer.

Omega XL Reviews and Final Thoughts

On the official Omega XL website, there are tons of positive reviews. The supplement relieved their symptoms and made their joints feel more comfortable, according to the majority of positive reviews.

On Amazon, Omega XL has received positive feedback and reviews, with many people praising the fact that it does not smell fishy, is easy to take, and reduces or eliminates joint pain. Most customers report being able to move more easily and with less or no discomfort, allowing them to resume some of their favorite activities.

Customers say Omega XL is a top joint health supplement; many stating they like that the key ingredients are backed up by clinical evidence.

Overall, OmegaXL is a highly rated and effective joint health supplement. Because of their use of ingredients that are statistically significant in reducing ache and inflammation, you can count on it to be a good quality, well-priced product with multiple proven benefits, according to findings when reviewing it.

Where to Buy Omega XL

Although it is recommended to purchase the Omega XL supplement directly from the manufacturer, it is also available to purchase on Amazon.

Omega XL comes in a bottle with 60 servings.
You can purchase the supplement in the following packages:

  • Introductory Package (60-capsules bottle + free bottle) – around $45.
  • 60-count capsules bottle– around $70.
  • Sport 60 capsules bottle – around $120.
  • 120 capsules bottle – around $130.
  • 300 capsules bottle – around $250.

Frequently Asked Questions

Omega XL is an omega-3 dietary health supplement that’s designed to support a healthy inflammatory response. The formula contains clinically-researched ingredients that help to support joint health, immune system function, and respiratory health. The product claims to offer relief from muscle soreness and recovery.
Omega XL is an all-natural supplement that contains more than 30 fatty acids in highly bioavailable forms. The active ingredients found in the supplement's formula include flaxseed oil, omega 3 fatty acids, vitamin E, green-lipped mussel oil, and olive oil.
Omega XL is free of common allergens, including gluten, maize, and dairy. Omega XL is viewed as safe to consume by healthy individuals as long as it’s taken as directed on the label of the supplement. Some side effects may include bloating, nausea, and loose stools.
Omega XL is a joint support supplement that is manufactured and distributed by the natural wellness products company Great HealthWorks. Their manufacturing facilities are located in Florida, United States. The company is known for producing and distributing clinically-researched health products.
On the company’s website, a single bottle of Omega XL is $39.95 plus a $4.95 shipping cost, totaling $44.90. Once you purchase your first bottle, the company automatically enrolls you in an auto-ship program that sends a monthly bottle for the same price.
Omega XL omega supplement is only available to purchase on the manufacturers website. Great HealthWorks does offer a 90-day money back guarantee for buyers who are not completely satisfied with their products. The refund amount does not cover shipping costs.


  1. Chaddha, A., & Eagle, K. A. (2015). Omega-3 fatty acids and heart health. Circulation, 132(22), e350-e352.
  2. Goldberg, R. J., & Katz, J. (2007). A meta-analysis of the analgesic effects of omega-3 polyunsaturated fatty acid supplementation for inflammatory joint pain. Pain, 129(1-2), 210-223.
  3. Kurutas, E. B. (2015). The importance of antioxidants which play the role in cellular response against oxidative/nitrosative stress: current state. Nutrition journal, 15(1), 1-22.
  4. Ozgocmen, S., Ozyurt, H., Sogut, S., Akyol, O., Ardicoglu, O., & Yildizhan, H. (2006). Antioxidant status, lipid peroxidation and nitric oxide in fibromyalgia: etiologic and therapeutic concerns. Rheumatology international, 26(7), 598-603.
  5. Peet, M., & Stokes, C. (2005). Omega-3 fatty acids in the treatment of psychiatric disorders. Drugs, 65(8), 1051-1059.
  6. Mori, T. A. (2014). Omega-3 fatty acids and cardiovascular disease: epidemiology and effects on cardiometabolic risk factors. Food & function, 5(9), 2004-2019.
  7. N GREENHILL, P DAVIS. Anti-inflammatory Activity of an Oil Derived from Perna canaliculus (New Zealand Green-lipped Mussel).. The Internet Journal of Alternative Medicine. 2008 Volume 8 Number 1.
  8. Moyad, M. A. (2005, January). An introduction to dietary/supplemental omega-3 fatty acids for general health and prevention: part II. In Urologic Oncology: Seminars and Original Investigations (Vol. 23, No. 1, pp. 36-48). Elsevier.
  9. Chin, K. Y., & Ima-Nirwana, S. (2018). The role of vitamin E in preventing and treating osteoarthritis–a review of the current evidence. Frontiers in pharmacology, 9, 946.
  10. Zeratsky, A. F. K. (2009). Nutrition and healthy eating. MayoClinic. com. Mayo Clinic, 27.
  11. Hekmatpou, D., Mortaji, S., Rezaei, M., & Shaikhi, M. (2020). The Effectiveness of Olive Oil in Controlling Morning Inflammatory Pain of Phalanges and Knees Among Women With Rheumatoid Arthritis: A Randomized Clinical Trial. Rehabilitation nursing : the official journal of the Association of Rehabilitation Nurses, 45(2), 106–113.

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