Life Extension Magnesium Reviews, Ingredients, Does It Work?

Edited and medically reviewed by ✔️ Team of BestInSupplements | Written by Katelyn Johnson (B.S. and M.S. in Nutrition Science)

Does Life Extension Magnesium live up to its claims? Is it safe? Will it help me? Read our comprehensive and unbiased supplement review of its health benefits and ingredients.

Review of Life Extension Magnesium

Magnesium is one of the most vital minerals in the body. Magnesium functions as a cofactor in over 300 biochemical reactions that control metabolic events such as muscular contraction, neuron function, and carbohydrate metabolism 1.

This component, which is found in the form of a supplement in Life Extension Magnesium, also aids in the regulation of ATP activation, protein synthesis, blood pressure control, and blood sugar levels 2.

What’s more, magnesium promotes heart and circulatory health, supports immunity, and strengthens bones, while also regulating levels of many important nutrients in your body, such as calcium, potassium, and zinc.

Magnesium also boosts HDL (good) cholesterol levels and helps to lower blood LDL (bad) cholesterol levels by suppressing LDL oxidation. Oxidized LDL promotes atherosclerosis, which is a buildup of plaque (cholesterol-rich fatty deposits) in your arteries 3.

Deficiency has been linked to the progression of various diseases such as hypertension, hypoglycemia, and insulin resistance 3. Magnesium is required by both children and adults for normal bodily function. However, for some, dietary intake of this nutrient is insufficient, and they must rely on magnesium supplements to fulfill the nutritional gap.

A magnesium supplement like Life Extension's Magnesium Caps 500 mg may be the ideal solution for those who just can’t seem to meet their daily magnesium needs through their diets. And this supplement have one of the highest elemental magnesium concentrations per capsule available with 119% of the daily value (DV) of magnesium 1.

Magnesium Caps 500 mg by Life Extension comes in a container with 100 vegetarian capsules. Life Extension pills are made with high-quality components that enhance longevity and wellness. When it comes to formulations, its laboratory works hard to stay ahead of the competition.

Life Extension's Magnesium Benefits

Life Extensions magnesium supplement provides a daily supply of magnesium to boost heart and bone health, enhance energy metabolism, and preserve brain and nervous system functions. This supplement also supports metabolic health by promoting healthy immune system functions and maintaining healthy blood pressure and lipid levels 3-6.

Blood Pressure and Cardiovascular Health

Magnesium promotes healthy cardiovascular function and blood flow by relaxing the smooth muscles within blood vessels and reducing peripheral vascular resistance (vasoconstriction). It also aids in the maintenance of already good blood pressure levels.

This component supports cardiovascular health and aids in normal muscle function. It promotes a healthy inflammatory response and endothelial function, as well as inhibiting oxidative stress 3.

Brain and Nervous System Health

Magnesium aids in the normal operation of the nervous system. It is essential for healthy functioning neurons and promotes brain health 4.

It influences norepinephrine levels in the blood, as well as the synthesis of serotonin and nitric oxide. It can also influence the signaling of neurotransmitters, which makes magnesium an appropriate supplement to promote a positive mood 5.

Many people take magnesium to treat headaches, particularly severe migraines. And according to some research, magnesium may even aid with relieving anxiety.

Bone Density and Skeletal Structure Health

Magnesium has a favorable effect on bone health and aids in the preservation of healthy teeth. Magnesium, together with calcium and other minerals, is required for a healthy bone matrix 6.

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Combined, these nutrients have the ability to metabolize minerals required for bone repair and reconstruction. A well-mineralized bone matrix aids in the maintenance of strong, healthy bones.

Metabolic Health

Magnesium consumption also enhances a variety of metabolic factors. It is shown to have a positive effect on serum lipid profiles, inflammation, endothelial dysfunction, immune regulation, and protects against oxidative stress 7,8.

It helps with normalizing energy-yielding systems in the body, which aids in the alleviation of tiredness and weariness 9.

Life Extension Magnesium Caps Ingredients

Ingredients of Life Extension Magnesium Caps

Each capsule of Life Extension Magnesium supplement is non-GMO-verified and includes four types of magnesium: magnesium oxide, magnesium citrate, magnesium succinate, and magnesium glycinate chelate.

As a result, it is one of the most complete magnesium supplements available. Let's analyze in depth each one of it's ingredients:

Magnesium Oxide

Magnesium oxide is a salt formed by the combination of magnesium and oxygen.

This form is often used to provide temporary relief from unpleasant digestive problems such as heartburn, indigestion, and constipation. It can also be used to manage and prevent migraine headaches 1.

Magnesium Citrate

Magnesium citrate is magnesium combined with citric acid. Magnesium citrate is the most commonly used form of magnesium in supplements. Research indicates that it is one of the most bioavailable forms of magnesium, which means it is more effectively absorbed in your digestive tract than in other forms.

It is widely used to restore low magnesium levels. Because of its natural laxative effect, it is occasionally used to treat constipation at greater doses. It also has potential calming effects and is promoted to ease symptoms of depression and anxiety 10.

Magnesium Succinate

Magnesium succinate is magnesium that has been bound with succinic acid. This compound supplies the body with a Krebs cycle (the body’s main supply of cellular energy) mediator and is important in energy production and the regeneration of muscle fiber and nerve endings 11.

Magnesium Lysyl Glycinate Chelate

Magnesium lysyl glycinate is magnesium that has been bound to the amino acid glycine. Magnesium glycinate is often marketed for its calming properties 12. It has been shown to promote sleep, treat inflammatory disorders such as heart disease and diabetes, and also aid in reducing symptoms associated with anxiety, depression, tension, and insomnia.

This form is known for its high absorption rates and also the magnesium form with the lowest potential for causing a laxative effect.

Other ingredients in Life Extension Magnesium caps include vegetable cellulose (capsule), microcrystalline cellulose, stearic acid, silica, citric acid.

Is Life Extension Magnesium Safe?

Because of the value transparency and quality of Life Extension brand, each of their items comes with a Certificate of Analysis that permits you to verify the product's quality and accuracy.

Life Extension's Magnesium Caps, which are manufactured in an NSF International-registered GMP facility, are not only safe but also one of the most cost-effective solutions when searching for a magnesium supplement.

One particular ingredient that consumers may initially be concerned about in these pills is microcrystalline cellulose due to its use as a synthetic binding agent in supplements. That said, the FDA has approved microcrystalline cellulose as a GRAS (generally recognized as safe) bulking (filling) agent 13.

Overall, very minimal amounts of inactive compounds – like microcrystalline cellulose - are used to improve the overall quality of supplements the following manufacturing in order to ensure the products meet the intended expiration date. Most importantly, the amount used in products like Life Extensions magnesium caps is not harmful to human health.

Magnesium RDA (recommended daily allowance) for men is 420 mg and for women, it is 320 mg. 1 Dose up to 1500 mg of magnesium has been justified in supplement use with no documented toxicity. However, if you take more than the daily recommended serving size as indicated on the product label, it may lead to loose stools.

Life Extension Magnesium Side Effects

Taking magnesium supplements is unlikely to have major negative effects, and there appears to be enough evidence to suggest supplementing is very beneficial. Although uncommon, some of the side effects of consuming too much magnesium are stomach cramping, nausea, and diarrhea.

Despite the fact that it has numerous benefits, magnesium citrate is typically suggested as a laxative 10. You may suffer diarrhea if you have a sensitive stomach after taking this product. To avoid this, talk to your doctor about your gastrointestinal health before making a purchase.

Who Should Use Life Extension's Magnesium?

Life Extensions' magnesium pills are great for those wanting or needing a daily boost of magnesium without adding calories. These gluten-free and vegetarian-friendly pills are suitable for individuals who live a plant-based lifestyle and/or follow a gluten-free diet.

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Magnesium is necessary for good health, making Life Extension’s Magnesium capsules a great supplement for anyone pursuing a fitness goal. Magnesium helps your bones and muscles function, addresses muscle cramps, and enhances natural energy production. This allows your body to keep up with the demands of a rigorous workout regimen without worry or becoming fatigued.

Life Extension Magnesium Reviews and Final Thoughts

Labdoor, an online review site committed to assisting consumers in better understanding dietary supplement products, examined a wide variety of popular magnesium supplements and ranked Life Extension's Magnesium Caps (500mg) as the top magnesium supplement with an overall A grade 14.

The Magnesium Caps from Life Extension passed all of the Labdoor purity tests. It also exceeded the magnesium label claim by 4.0 percent. Life Extension Magnesium Caps ranked first in quality and 12th in value.

Overall, Life Extension is a brand that strives to live up to its name by offering high-quality, natural products that support longer and healthier lives for its consumers. Their magnesium caps supplement received 4.9 out of 5 stars with over 300 reviews on PowerReviews.

The most positive feedback included that this magnesium supplement is effective, easy on the stomach, and overall easy to take/swallow. Additionally, PowerReviews claim that 99% of reviewers stated they would recommend this supplement to a friend.

Purchasing Life Extension Magnesium Caps is well worth the cost if you want the finest quality, most effective, and most potent magnesium supplement on the market.

Where To Buy Life Extension Magnesium Capsules

This is one of the greatest low-cost magnesium supplements available. The Life Extension Magnesium can provide numerous general health benefits at a relatively affordable cost.

The average cost of a 30-day supply (each bottle contains 100 pills; 500mg per serving) of Life Extension Magnesium caps is around $9. The intended serving is 1-3 pills daily - so one bottle has the potential to last a buyer more than three months.

Life Extension Magnesium Capsules can be purchased on their website – – and from various online vendors, such as Amazon, The Vitamin Shoppe, iHerb, and Vitacost. As well as in person, from stores like Walmart, CVS, GNC, Target, and Walgreens.

Life Extension
Life Extension supplements have been produced with the hope that these will be able to supply all deficient nutrients in the body and help gain better health.

Frequently Asked Questions

Life Extension Magnesium is a health supplement that contains the essential mineral, magnesium. The human body requires magnesium for a wide variety of functions. Magnesium contributes to muscle and nerve functions, cardiovascular, immune, and circulatory system health. Magnesium also supports protein synthesis and energy metabolism.
Life Extension Magnesium is made with high-quality compounds that encourage longevity and optimal health in every consumer. The manufacturer's research and development lab strives to maintain its leading position in the supplement industry by creating innovative formulas that are backed by science.
Magnesium is generally safe and tolerated for most people if they take it in the right amounts. Magnesium supplements may cause nausea, vomiting, or diarrhea. Magnesium can be dangerous if consumed in large quantities, potentially causing an irregular pulse, low blood pressure, disorientation, and sluggish breathing.
Life Extension Magnesium is manufactured by Life Extension, which is a well-known brand for producing high-quality, clean, and effective nutritional supplements. They invest a lot of time and money on researching and developing innovative formulas, as well as testing their products for quality, consistency, potency, and purity.
When it comes to pricing, Life Extensions Magnesium supplement is middle-of-the-road compared to other magnesium supplements. Depending on the purchase location, serving size, and quantity, you can find this supplement for sale with prices ranging between $10 to $30.
You can buy Life Extension Magnesium and all of their other products at their retail location in Florida called The Health and Wellness Market. You can also purchase this supplement from retail shops like GNC and The Vitamin Shoppe, as well as larger retail chains like Target, Walmart, and Walgreens.


  1. Kumssa, D. B., Joy, E. J., Ander, E. L., Watts, M. J., Young, S. D., Rosanoff, A., ... & Broadley, M. R. (2015). Global magnesium supply in the food chain. Crop and Pasture Science, 66(12), 1278-1289.
  2. Tangvoraphonkchai, K., & Davenport, A. (2018). Magnesium and cardiovascular disease. Advances in chronic kidney disease, 25(3), 251-260.
  3. Zhang, X., Li, Y., Del Gobbo, L. C., Rosanoff, A., Wang, J., Zhang, W., & Song, Y. (2016). Effects of magnesium supplementation on blood pressure: a meta-analysis of randomized double-blind placebo-controlled trials. Hypertension, 68(2), 324-333.
  4. Vink, R. (2016). Magnesium in the CNS: recent advances and developments. Magnesium research, 29(3), 95-101.
  5. Romani, A. M., Ghabriel, M. N., Vink, R., Rubin, H., Trapani, V., Mastrototaro, L., ... & Murk, H. (2011). Magnesium in the Central Nervous System.
  6. Erem, S., Atfi, A., & Razzaque, M. S. (2019). Anabolic effects of vitamin D and magnesium in aging bone. The Journal of steroid biochemistry and molecular biology, 193, 105400.
  7. Simental-Mendia, L. E., Sahebkar, A., Rodriguez-Moran, M., & Guerrero-Romero, F. (2016). A systematic review and meta-analysis of randomized controlled trials on the effects of magnesium supplementation on insulin sensitivity and glucose control. Pharmacological research, 111, 272-282.
  8. Iida, M., Harada, S., & Takebayashi, T. (2019). Application of metabolomics to epidemiological studies of atherosclerosis and cardiovascular disease. Journal of atherosclerosis and thrombosis, RV17036
  9. Chang, W. S., Liu, L. C., Hsiao, C. L., Su, C. H., Wang, H. C., Ji, H. X., ... & Bau, D. T. (2016). The contributions of the tissue inhibitor of metalloproteinase-1 genotypes to triple negative breast cancer risk. BioMedicine, 6(1), 1-6
  10. Nica, A. S., Caramoci, A., Vasilescu, M., Ionescu, A. M., Paduraru, D., & Mazilu, V. (2015). Magnesium supplementation in top athletes-effects and recommendations. Sports Medicine Journal/Medicina Sportivâ, 11(1).
  11. European Food Safety Authority (EFSA). (2009). Calcium acetate, calcium pyruvate, calcium succinate, magnesium pyruvate magnesium succinate and potassium malate added for nutritional purposes to food supplements. EFSA Journal, 7(6), 1088.
  12. Boyle, N. B., Lawton, C., & Dye, L. (2017). The effects of magnesium supplementation on subjective anxiety and stress—a systematic review. Nutrients, 9(5), 429.
  13. Zhong, F., & Nsor-Atindana, J. (2021). Microcrystalline cellulose and nanocrystalline cellulose. In Handbook of Hydrocolloids (pp. 509-536). Woodhead Publishing.

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