The Best Hyaluronic Acid Supplements You Can Buy

Edited and medically reviewed by ✔️ Team of BestInSupplements | Written by Katelyn Johnson (B.S. and M.S. in Nutrition Science)

The best hyaluronic acid supplements are designed with women in mind. Check our review to learn more about how they help reduce wrinkles and lines on your face and help the skin to stretch and flex.

best hyaluronic acid supplements

Hyaluronic acid is a naturally occurring water-soluble compound found mostly in the skin, joints, tendons, eye sockets, and other connective tissues. Its primary function is to attract and hold moisture in order to cushion and lubricate joints and connective tissues 1.

As we become older, our natural production of hyaluronic acid decreases dramatically - up to 50% by the time we reach 50 years old. Low hormone levels, sun exposure, smoking, alcohol, a poor diet, and pollution all have a negative impact on levels 2.

Combine the Hyaluronic Acid with Collagen Supplements from NeoCell 

It's been widely used as a supplement to help with joint health and eye discomfort and treat or prevent age-related health issues. Because levels of hyaluronic acid decline with aging, boosting intake improves the body's natural production, according to studies 3.

Supplementing with hyaluronic acid has been shown to protect joints and cartilage, reduce pain-related nerve impulses and sensitivity, alter immune cell behavior, aid in the natural detoxification process, and serve as a structural component4,5.

Best Hyaluronic Acid Supplements You Can Find In The Market

You can supplement your body's supply of hyaluronic acid if it is no longer producing enough. With a variety of hyaluronic acid supplements to select from, the following list compiles the best Hyaluronic Acid supplements from brands with a track record of quality and purity.

NatureBell Hyaluronic Acid Supplements

NatureBell’s Hyaluronic Acid is an ultra-premium hyaluronic acid supplement and one of the most popular on the market. Their product, which includes hyaluronic acid in sodium hyaluronate capsules, each containing 250 mg of hyaluronic acid and 25 mg of vitamin C per serving, is designed to enhance absorption for faster results.

naturebell hyaluronic acid supplements

Vitamin C is recognized for its antioxidant capabilities, which protect our cells from the harmful effects of free radicals. The combination of hyaluronic acid and vitamin C guarantees that this supplement will protect your skin from sun damage and fade skin discoloration, both of which decrease aging signs 6.

NatureBell promotes skin, hair, and nail hydration. It's utilized to produce better hair, nails, cartilage, and younger and more beautiful skin. It also hydrates and nourishes the scalp's deep layer, resulting in bright, healthy hair and a moisturized scalp.

Their product has received nearly 6,000 global ratings on Amazon. Out of these reviews, it has upheld a rating of 4.6/5 stars, with 77% being 5 stars.

The product has been third-party tested and verified in the United States for purity and certified as all-natural, vegan, and free of GMOs, Gluten, sugar, soy, and tree nuts.

Amazing Formulas Hyaluronic Acid by Amazing Nutrition

Amazing Formulas Hyaluronic Acid is one of the best hyaluronic acid supplements available. Each Hyaluronic Acid pill from Amazing Nutrition includes 200 milligrams of hyaluronic acid, which is the ideal dose for customers to get all of the advantages of hyaluronic acid with a simple hyaluronic acid supplement.

amazing formulas hyaluronic acid

The hyaluronic acid supplement from Amazing Formulas ensures adequate levels of hydration, which has been shown to improve skin health and appearance by softening premature lines and wrinkles. Hydration also promotes healthy, lubricated joints and connective tissue. Additionally, their formula stimulates cell regeneration and structure, improving mobility and strengthening connective tissue and joints.

Amazing Nutrition's hyaluronic acid supplement is GMP compliant and non-GMO. They are also free of fish, eggs, dairy, soy, tree nuts, and gluten, making them ideal for most dietary regimens. When looking at Amazon’s verified customer reviews, Amazing Nutrition has 4.7/5 stars with over 9,000 ratings, with 72% being 5 stars.

Horbäach’s Hyaluronic Acid

Horbäach’s Hyaluronic Acid is one of the most bioavailable hyaluronic acid supplements with 200 mg of total hyaluronic acid. It is currently one of the most effective supplements of its kind to enhance the appearance of skin and promote healthy connective tissue. Additionally, if you are looking to boost your intake of hyaluronic acid, this supplement is an excellent choice as the formula offers a high supplement dosage.

horbaach hyaluronic acid supplement

Horbäach’s hyaluronic acid capsules are non-GMO, third-party tested and confirmed, and packed in a GMP-certified United Stated facility. Furthermore, it is free of gluten, lactose, milk, yeast, wheat, artificial sweeteners, artificial flavors, and preservatives, as well as other common allergies.

This is a well-rounded supplement that can be consumed in addition to other vitamins and supplements like collagen, vitamin C, or glucosamine chondroitin to help with joint pain. On Amazon, out of 2,600 ratings, it maintains 4.6/5 stars with 75% being 5 stars.

For Better Results Combine Your Hyaluronic Acid Supplements with Nature Made Vitamin C

Jarrow Formulas Hyaluronic Acid

The Hyaluronic Acid supplement from Jarrow Formulas is an all-natural, pure hyaluronic acid supplement with clinical documentation verifying its low molecular weight and bioavailability via biological fermentation. Their formula contains 120 mg of hyaluronic acid that is scientifically validated to improve skin hydration and adequately lubricate joints and connective tissue 7.

jarrow formulas hyaluronic acid

Hyaluronic acid is a naturally occurring compound in the body and vital to connective tissue structure because it fills the gaps between skin cells and other tissues. Because hyaluronic acid is found in synovial fluid, which lubricates and absorbs shock impact in joints, Jarrow Formulas Hyaluronic Acid promotes joint health by keeping joints lubricated and flexible.

Jarrow Formulas supports skin health by keeping it hydrated, helping to create collagen and combating free radical damage to the skin, which may cause wrinkles, as well as promoting skin injury healing. Their supplement also supports eye health as hyaluronic acid fills the vitreous body of the eye's inner chamber, which effectively lubricates and protects the eyes. On Amazon, out of 1,400 ratings, it maintains 4.6/5 stars with 80% being 5 stars.

NeoCell Hyaluronic Acid

NeoCell’s Hyaluronic Acid offers one of the best hyaluronic acid supplements for hydrating the skin. It provides one of the most bioavailable forms of hyaluronic acid that holds 1,000 times its weight in water for cushioning of joints.

neocell hyaluronic acidIt is a powerful aid in skin hydration and wrinkle reduction and activates your inner beauty by increasing lubrication in joints and hydrating the skin for a better look. This is a top seller and one of the best hyaluronic acid supplements on the market.

This formula helps in cell turnover and lubricates the surface of the eye. According to the company this product is clinically shown to increase skin hydration. On Amazon, out of 1,100 ratings, it maintains 4.7/5 stars with 80% being 5 stars.

Best Naturals Hyaluronic Acid

Best Naturals Hyaluronic Acid is a top-rated supplement with 100 mg of hyaluronic acid per serving. Also included is chondroitin sulfate, glucosamine sulfate, and a bioavailable form of type II collagen for improved absorption. It helps to lubricate the skin, wrinkles, and dry eyes, as well as alleviate pain and stiffness in the joints 8.

best naturals hyaluronic acidChondroitin sulfate and glucosamine sulfate are abundant in these hyaluronic acid capsules. These nutrients are found in the knees, hips, and other mobile joints, and they're necessary for maintaining healthy, lubricated joints and movement.

Best Naturals' hyaluronic acid improves the structure and tone of the skin by boosting connective tissue and moisturizing the skin, which helps to achieve the best impact on sore joints and combat symptoms of aging.

More Supplement Alternatives When You Have Joint Pain

This supplement is free of artificial colors, flavors or sweeteners, preservatives, gluten yeast, fish, sugar, sodium, starch, corn, soy, egg, milk, and lactose. On Amazon, out of 630 ratings, it maintains 4.5/5 stars with 70% being 5 stars.

Purity Products Ultimate H.A. Formula

Purity Products' Ultimate H.A. Formula has a proprietary mix of BioCell type II hydrolyzed collagen, chondroitin sulfate, and hyaluronic acid to support healthy and attractive skin.

purity products ultimate h.a. formulaHyaluronic acid is an important component of the skin matrix that keeps the skin supple and moisturized. Ultimate H.A. enhances appearance by decreasing fine lines and wrinkles and increasing skin hydration from the inside. This helps to preserve the integrity and texture of the skin 9.

This is one of the finest hyaluronic acid supplements on the market since it has been clinically shown to minimize wrinkles, fine lines, and improve skin microcirculation. Collagen and hyaluronic acid work together to help develop cartilage and joint structure, as well as improve joint comfort and mobility, support tendons and ligaments, and promote joint lubrication and proper shock absorption capacity. On Amazon, out of 760 ratings, it maintains 4.4/5 stars with 69% being 5 stars.

Frequently Asked Questions

The best hyaluronic acid supplements are designed to support the body’s natural production of hyaluronic acid in order to improve the health and maintenance of skin and joints. Hyaluronic acid supports a healthy hydration status in the body, which further supports strong, mobile, and flexible joints and skin.
The main ingredients in the best hyaluronic acid supplements will consist of natural hyaluronic acid, which will typically be the main active ingredient as the supplement name suggests. They may also include other vitamins and minerals known to support healthy production of hyaluronic acid.
You can choose the best hyaluronic acid supplement by reviewing the product's label and the ingredients used to formulate the supplement. Choose supplements manufactured by a reputable brand that utilizes third party labs to test their ingredients and formulas for quality, potency, and effectiveness.
The best hyaluronic acid supplements are available in multiple forms. You can find them in capsule, tablet, or gummy form. They are also available as an oil or powder. The benefits of taking a hyaluronic acid supplement usually depends on the concentration and potency of the ingredients in the formula.
Avoid hyaluronic acid supplements that are not made with natural ingredients or tested by third party labs for quality and purity. Also, avoid hyaluronic acid supplements that do not contain an effective dose of hyaluronic acid or do not contain scientifically validated ingredients.
In general, hyaluronic acid supplements are viewed as safe to consume by healthy individuals when taken as directed on the products label. This is especially true if it’s made with natural ingredients. That said, if side effects are experienced, common ones include nausea, headaches, and digestive distress.


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  2. Cao, C., Xiao, Z., Wu, Y., & Ge, C. (2020). Diet and Skin Aging-From the Perspective of Food Nutrition. Nutrients, 12(3), 870.
  3. Litwiniuk, M., Krejner, A., Speyrer, M. S., Gauto, A. R., & Grzela, T. (2016). Hyaluronic acid in inflammation and tissue regeneration. Wounds, 28(3), 78-88.
  4. Palmieri, B., Merighi, A., Corbascio, D., Rottigni, V., Fistetto, G., & Esposito, A. (2013). Fixed combination of hyaluronic acid and chondroitin-sulfate oral formulation in a randomized double blind, placebo controlled study for the treatment of symptoms in patients with non-erosive gastroesophageal reflux. European review for medical and pharmacological sciences, 17(24), 3272–3278.
  5. Oe, M., Sakai, S., Yoshida, H., Okado, N., Kaneda, H., Masuda, Y., & Urushibata, O. (2017). Oral hyaluronan relieves wrinkles: a double-blinded, placebo-controlled study over a 12-week period. Clinical, cosmetic and investigational dermatology, 10, 267.
  6. Bucay, V. W. (2021). Cosmeceuticals Using Peptides, Amino Acids, Glycosaminoglycans, and Other Active Ingredients. In Cosmeceuticals (Vol. 5, pp. 63-72). Karger Publishers.
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  8. Jerosch J. (2011). Effects of Glucosamine and Chondroitin Sulfate on Cartilage Metabolism in OA: Outlook on Other Nutrient Partners Especially Omega-3 Fatty Acids. International journal of rheumatology, 2011, 969012.
  9. Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-endocrinology, 4(3), 253–258.

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